– DCDAPH (1,1-dicyano-6-(4-N,N-dimethylaminophenyl)-1,3,5-hexatriene) is a far-red fluorescent probe that has proved to have affinity to Aβ plaques. It has been used for fluorescent staining of brain sections, as well as in vivo detection of Aβ_1-42 aggregates by small animal near-IR imaging.  DCDAPH has high affinity (Ki= 37 nM, Kd=27 nM) to Aβ_1-42 aggregates. 

 
• Dark purple solid
 
• &lamba;_Ex/&lamba;_Em = 597/665 nm (PBS)
 
• Store at -20°C and protect from light, especially in solution
 
• C16H15N3
 
• MW: 249.31
 

Handling

Store with desiccant; Protect from light