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TRPV4 agonist-1 (free base)
$72 – $1,180
Products Details
Product Description
– TRPV4 agonist-1 free base is a transient receptor potential vanilloid 4 (TRPV4) agonist with an EC50 of 60 nM in the hTRPV4 Ca2+ assay[1].
Web ID
– HY-114400
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H22F2N4O2
References
– [1]Atobe M, et al. Discovery of Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonists as Regulators of Chondrogenic Differentiation: Identification of Quinazolin-4(3 H)-ones and in Vivo Studies on a Surgically Induced Rat Model of Osteoarthritis. J Med Chem. 2019 Jan 28.
CAS Number
– 2314467-59-7
Molecular Weight
– 448.46
Compound Purity
– 99.58
SMILES
– O=C1N(C2=CC=C(OC3=CC=C(F)C=C3)C=C2)C(N4CCN(C)CC4)=NC5=C(F)C=CC=C51
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 83.33 mg/mL (ultrasonic)
Target
– TRP Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
