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Products Details
Product Description
– Steroid sulfatase/17β-HSD1-IN-3 (compound 19) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-3 irreversibly inhibits hSTS activity with anIC50 value of 27 nM. Steroid sulfatase/17β-HSD1-IN-3 can be used in the study of endometriosis and other estrogen-dependent diseases[1].
Web ID
– HY-151201
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H17ClN2O5S
References
– [1]Abdelrahman Mohamed, et al. Dual Targeting of Steroid Sulfatase and 17β-Hydroxysteroid Dehydrogenase Type 1 by a Novel Drug-Prodrug Approach: A Potential Therapeutic Option for the Treatment of Endometriosis. J Med Chem. 2022 Aug 22.
Molecular Weight
– 420.87
SMILES
– O=S(OC1=CC=C(C2=CC=C(C(N(C)C3=CC=CC=C3C)=O)O2)C(Cl)=C1)(N)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Others
Pathway
– Others
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
