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Products Details
Product Description
– SphK1-IN-1 (compound 48) is a SphK1 inhibitor with effective antitumor activity. SphK1-IN-1 inhibits SphK1 ATPase with an IC50 value of 4.02 μM. SphK1-IN-1 can be used for the research of cancer[1].
Web ID
– HY-143296
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H22N6O2
References
– [1]A. Galal, et al. Design and synthesis of new pyrazolylbenzimidazoles as sphingosine kinase-1 inhibitors. (2021) 1614–1634.
Molecular Weight
– 402.45
SMILES
– CC1=NN(C(N2CCCCC2)=C1C3=NC4=CC([N+]([O-])=O)=CC=C4N3)C5=CC=CC=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– SphK
Isoform
– SphK1
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
