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Products Details
Product Description
– Sirt2-IN-7 (compound 22) is a selective inhibitor of SIRT2. Sirt2-IN-7 inhibits SIRT2 with an IC50 value and a Ki value of 178.2 nM and 154.3 nM, respectively. Sirt2-IN-7 can be used for the research of cancer[1].
Web ID
– HY-151185
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C40H68Cl2N6O6S
References
– [1]Kalbas D, et al. Small Changes Make the Difference for SIRT2: Two Different Binding Modes for 3-Arylmercapto-Acylated Lysine Derivatives. Biochemistry. 2022 Aug 16. doi: 10.1021/acs.biochem.2c00211. Epub ahead of print. PMID: 35972884.
Molecular Weight
– 831.98
SMILES
– CCCCCCCCCCCCC[C@H](SC1=CC=C(C(Cl)=C1)Cl)CC(N[Ac-KKT-NH2])=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Sirtuin
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
