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Salubrinal

SKU T3045-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 56 CAD through 1,744 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T3045

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H17Cl3N4OS

Citations

– 1. Meng C, Zhang J, Dang B, et al. PERK pathway activation promotes intracerebral hemorrhage induced secondary brain injury by inducing neuronal apoptosis both in vivo and in vitro. Frontiers in Neuroscience. 2018 Feb 28;12:111 2. Zhao Y, Feng Y, Ye Q, et al.The oral microbiome in young women at different stages of periodontitis: Prevotella dominant in stage III periodontitis.Frontiers in Cellular and Infection Microbiology.2022 3. Berthier A, Gheeraert C, Johanns M, et al.The Molecular Circadian Clock Is a Target of Anti-cancer Translation Inhibitors.Journal of Biological Rhythms.2023: 07487304231202561.

References

– Boyce M, et al. Science, 2005, 307(5711), 935-939.

CAS Number

– 405060-95-9

Molecular Weight

– C21H17Cl3N4OS

Compound Purity

– 0.9997

SMILES

– ClC(Cl)(Cl)C(NC(=S)NC1=CC=CC2=CC=CN=C12)NC(=O)C=CC1=CC=CC=C1

Pathway

– Apoptosis|||Metabolism|||Autophagy|||Microbiology/Virology

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.