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(-)-(S)-B-973B
$150 – $1,780
Products Details
Product Description
– (-)-(S)-B-973B is a potent allosteric agonist and positive allosteric modulator of α7 nAChR, with antinociceptive activity[1].
Web ID
– HY-114269
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C24H26F2N6O
References
– [1]Garai S, et al. B-973, a Novel α7 nAChR Ago-PAM: Racemic and Asymmetric Synthesis, Electrophysiological Studies, and in Vivo Evaluation. ACS Med Chem Lett. 2018 Oct 11;9(11):1144-1148.
CAS Number
– 2244989-34-0
Molecular Weight
– 452.50
Compound Purity
– 99.22
SMILES
– O=C(N[C@H](C1=NC(N2CCN(C3=NC=CC=C3)CC2)=CN=C1)C)CCC4=CC=C(F)C(F)=C4
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 67.5 mg/mL (ultrasonic)
Target
– nAChR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
