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Products Details
Product Description
– ROS1-IN-1 (Compound 31) is a potent and selective ROS1 kinase inhibitor with an IC50 of 0.097 μM[1].
Web ID
– HY-150974
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C17H15ClN6S
References
– [1]Petrović D, et al. Virtual Screening in the Cloud Identifies Potent and Selective ROS1 Kinase Inhibitors. J Chem Inf Model. 2022 Aug 3.
CAS Number
– 2883232-34-4
Molecular Weight
– 370.86
SMILES
– CC1=NC(N(CC2=CC=C(C(Cl)=C2)C#N)C)=NC(NC3=NC=CS3)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ROS Kinase
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
