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Products Details
Product Description
– MraY-IN-3 (12a) is a potent bacterial translocase MraY inhibitor with an IC50 value of 140 µM. MraY-IN-3 acts on E. coli K12, B. subtilis W23 and P. fluorescens Pf-5 with the MIC50 values of 7 µg/mL, 12 µg/mL, and 46 µg/mL, respectively[1].
Web ID
– HY-151357
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C35H45N3O5
References
– [1]Rachel V Kerr, et al. Peptidomimetic analogues of an Arg-Trp-x-x-Trp motif responsible for interaction of translocase MraY with bacteriophage Ï•X174 lysis protein E. Bioorg Med Chem. 2021 Dec 15;52:116502.
CAS Number
– 2851534-52-4
Molecular Weight
– 587.75
SMILES
– CCCCCCC(N(C1=CC(OCC2=CC=CC=C2)=C(C=C1)C(N[C@H](C(OC)=O)CCCCN)=O)CC3=CC=CC=C3)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
