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Products Details
Product Description
– LasR-IN-2 is a LasR inhibitor that forms H-bonding with TRY-56 residue. LasR-IN-2 can be used in the research of bacterial infection, neutropenia, severe burns and chronic lung disease in cystic fibrosis (CF)[1].
Web ID
– HY-151164
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H16ClN3O2
References
– [1]Rehab H Abd El-Aleam, et al. Design and synthesis of novel benzimidazole derivatives as potential Pseudomonas aeruginosa anti-biofilm agents inhibiting LasR: Evidence from comprehensive molecular dynamics simulation and in vitro investigation. Eur J Med Chem. 2022 Aug 5;241:114629.
Molecular Weight
– 377.82
SMILES
– O=C(NC1=CC=CC=C1)COC2=CC=C(C3=NC4=CC(Cl)=CC=C4N3)C=C2
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
