IAXO-102

SKU T11598-1 mg Category Small Compound Brand: TargetMol

Price range: 142 CAD through 2,160 CAD

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Product Description

– IAXO-102 is a TLR4 antagonist that negatively regulates TLR4 signaling by inhibiting MAPK and p65 NF-κB phosphorylation, as well as the expression of TLR4-dependent proinflammatory proteins. It also prevents the development of experimental abdominal aortic aneurysm.

Web ID

– T11598

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C35H71NO5

References

– Huggins C, et al. A novel small molecule TLR4 antagonist (IAXO-102) negatively regulates non-hematopoietic toll like receptor 4 signalling and inhibits aortic aneurysms development. Atherosclerosis. 2015 Oct;242(2):563-70.

CAS Number

– 1115270-63-7

Molecular Weight

– C35H71NO5

Compound Purity

– ≥98%

SMILES

– CCCCCCCCCCCCCCO[C@H]1[C@H](O)[C@@H](CN)O[C@H](OC)[C@@H]1OCCCCCCCCCCCCCC

Target

– PROTAC Linker

Pathway

– Immunology/Inflammation

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

IAXO-102

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