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Hispidol

$110$1,500

Products Details

Product Description

– Hispidol ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelial cells with an IC50 of 0.50 µM.

Web ID

– HY-102040

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C15H10O4

References

– [1]Kadayat TM, et al. Discovery and structure-activity relationship studies of 2-benzylidene-2,3-dihydro-1H-inden-1-one and benzofuran-3(2H)-one derivatives as a novel class of potential therapeutics for inflammatory bowel disease. Eur J Med Chem. 2017 Sep 8;137:575-597.

CAS Number

– 5786-54-9

Molecular Weight

– 254.24

Compound Purity

– 98.70

SMILES

– O=C1C2=CC=C(O)C=C2O/C1=CC3=CC=C(O)C=C3

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– DMSO : ≥ 100 mg/mL

Target

– TNF Receptor

Pathway

– Apoptosis

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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