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GRP78-IN-1
SKU
HY-145857-Get quote
Category Reference compound
Tags Apoptosis;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease, Apoptosis;HSP, Cancer
Products Details
Product Description
– GRP78-IN-1 exhibits several interactions with GRP78 residues with binding energy of -8.07 kcal/mol. GRP78-IN-1 shows the potent cytotoxic, anti-proliferative in cancer cells. GRP78-IN-1 exhibits promising apoptosis in breast cancer cells and stalls wound healing properties[1].
Web ID
– HY-145857
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H23FO3
References
– [1]Rasool JU, et al. Palladium catalyzed migratory heck coupling of arteannuin B and boronic acids: An approach towards the synthesis of antiproliferative agents in breast and lung cancer cells. Bioorg Chem. 2022, 122:105694.
Molecular Weight
– 342.40
SMILES
– [H][C@@]12CC[C@]3(O[C@H]3[C@@]14OC(C(CC5=CC=C(C=C5)F)=C4CC[C@H]2C)=O)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;HSP
Isoform
– HSP70
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.