Go 6983
Go 6983
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Go 6983

SKU T6313-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 58 CAD through 949 CAD

Products Details

Product Description

– Go 6983, a pan-PKC inhibitor, targets PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, with IC50 values of 7 nM, 7 nM, 6 nM, 10 nM, and 60 nM, respectively.

Web ID

– T6313

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H26N4O3

Citations

– 1. Fan Y L, Li B, Zhao H P, et al. A function of fascin1 in the colony formation of mouse embryonic stem cells. Stem Cells. 2020, 38(9): 1078-1090 2. Zhang Y, Wang Z, Cao J, et al. A Green and Blue Monochromatic Light Combination Therapy Reduces Oxidative Stress and Enhances B-Lymphocyte Proliferation through Promoting Melatonin Secretion. Oxidative Medicine and Cellular Longevity. 2021, 2021. 3. Ning S, Wang Z, Cao J, et al. Mel1c Mediated Monochromatic Light-Stimulated IGF-I Synthesis through the Intracellular Gαq/PKC/ERK Signaling Pathway. International journal of molecular sciences. 2019, 20(7): 1682. 4. Wang D, Wang Y, Di X, et al.Cortical tension drug screen links mitotic spindle integrity to Rho pathway.Current Biology.2023

References

– Gschwendt M, et al. FEBS Lett, 1996, 392(2), 77-80.

CAS Number

– 133053-19-7

Molecular Weight

– C26H26N4O3

Compound Purity

– 0.9985

SMILES

– COc1ccc2n(CCCN(C)C)cc(C3=C(C(=O)NC3=O)c3c[nH]c4ccccc34)c2c1

Pathway

– Cytoskeletal Signaling|||Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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