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Products Details
Product Description
– EB-0176 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC50s of 0.6439 and 0.0011 μM, respectively. EB-0176 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0176 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses[1].
Web ID
– HY-145275
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C23H33N5O7
References
– [1]Karade SS, et al. N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum α-Glucosidases I and II with Antiviral Activity. J Med Chem. 2021;64(24):18010-18024.
CAS Number
– 2758314-64-4
Molecular Weight
– 491.54
SMILES
– O[C@@H]1[C@H]([C@@H]([C@](O)(C[C@@H]1NCCCCCCNC2=C(C=C(C=C2)C3=NC=CC=N3)[N+]([O-])=O)CO)O)O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Glucosidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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