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Products Details
Product Description
– EB-0156 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC50s of 0.0479 and less than 0.001 μM, respectively. EB-0156 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0156 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses[1].
Web ID
– HY-145274
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C21H32N6O7
References
– [1]Karade SS, et al. N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum α-Glucosidases I and II with Antiviral Activity. J Med Chem. 2021;64(24):18010-18024.
CAS Number
– 2832824-43-6
Molecular Weight
– 480.51
SMILES
– O[C@@H]1[C@](O)(C[C@@H]([C@@H]([C@H]1O)O)NCCCCCCNC2=C(C=C(C=C2)N3N=CC=N3)[N+]([O-])=O)CO
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Glucosidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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