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Dexelvucitabine
$300 – $2,450
Products Details
Product Description
– Dexelvucitabine (Reverset; d-d4FC), a Cytidine (HY-B0158) analog, is an orally active nucleoside reverse transcriptase inhibitor. Dexelvucitabine is a powerful agent against HIV-1-resistant viruses containing a thymidine analog and/or M184V mutation in the viral polymerase. Dexelvucitabine is a 2′-Deoxycytidine antiretroviral agent[1].
Web ID
– HY-14920
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C9H10FN3O3
References
– [1]L Ma, et al. Pharmacokinetics of the antiviral agent beta-D-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine in rhesus monkeys. Antimicrob Agents Chemother. 1999 Feb;43(2):381-4.|[2]Brenda I Hernandez-Santiago, et al. Antiviral and cellular metabolism interactions between Dexelvucitabine and lamivudine. Antimicrob Agents Chemother. 2007 Jun;51(6):2130-5.
CAS Number
– 134379-77-4
Molecular Weight
– 227.19
Compound Purity
– 99.52
SMILES
– O=C1N(C=C(C(N)=N1)F)[C@]2([H])O[C@@H](C=C2)CO
Clinical Information
– Phase 2
Research Area
– Infection
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– HIV;Reverse Transcriptase
Isoform
– HIV-1
Pathway
– Anti-infection
Product type
– Reference compound
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