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DC661
Price range: 117 CAD through 1,808 CAD
Products Details
Product Description
– DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity.
Web ID
– T5538
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C31H39Cl2N5
Citations
– 1. Xu J, Su Z, Cheng X, et al. High PPT1 expression predicts poor clinical outcome and PPT1 inhibitor DC661 enhances sorafenib sensitivity in hepatocellular carcinoma. Cancer Cell International. 2022, 22(1): 1-20.
References
– Rebecca VW, et al. PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer. ancer Discov. 2019 Feb;9(2):220-229.
CAS Number
– 1872387-43-3
Molecular Weight
– C31H39Cl2N5
Compound Purity
– 0.9907
SMILES
– CN(CCCCCCNc1ccnc2cc(Cl)ccc12)CCCCCCNc1ccnc2cc(Cl)ccc12
Pathway
– Autophagy|||Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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