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Products Details
Product Description
– COX-2-IN-29 (Compound 15b) is a selective and orally active COX-2 inhibitor with an IC50 of 0.005 μM[1].
Web ID
– HY-150721
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H23FN2O6S2
References
– [1]Saletti M, et al. Novel analgesic/anti-inflammatory agents: 1, 5-Diarylpyrrole nitrooxyethyl sulfides and related compounds as Cyclooxygenase-2 inhibitors containing a nitric oxide donor moiety endowed with vasorelaxant properties. European Journal of Medicinal Chemistry, 2022: 114615.
Molecular Weight
– 494.56
SMILES
– O=[N+]([O-])OCCS(CCC1=C(C)N(C2=CC=C(F)C=C2)C(C3=CC=C(S(=O)(C)=O)C=C3)=C1)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– COX
Isoform
– COX-1;COX-2
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
