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Clofarabine
Price range: 58 CAD through 606 CAD
Products Details
Product Description
– Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.
Web ID
– T0297
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C10H11ClFN5O3
Citations
– 1. Berthier A, Gheeraert C, Johanns M, et al.The Molecular Circadian Clock Is a Target of Anti-cancer Translation Inhibitors.Journal of Biological Rhythms.2023: 07487304231202561.
References
– Bonate PL, et al. Nat Rev Drug Discov, 2006, 5(10), 855-863.
CAS Number
– 123318-82-1
Molecular Weight
– C10H11ClFN5O3
Compound Purity
– 0.9994
SMILES
– Nc1nc(Cl)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F
Target
– Autophagy|||ABC Transporter|||Adrenergic Receptor|||Potassium Channel|||MRP
Pathway
– Autophagy|||DNA Damage/DNA Repair|||Apoptosis|||Cell Cycle/Checkpoint
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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