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Products Details
Product Description
– Clathrin-IN-2 is potent inhibitor of clathrin mediated endocytosis (CME) with an IC50 value of 2.3 μM. Clathrin-IN-2 also has inhibitiory for dyn I GTPase with an IC50 value of 7.7 μM[1].
Web ID
– HY-152217
Shipping
– Room temperature
Molecular Formula
– C17H18Br2N2O
References
– [1]Peter J Cossar, et al. Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis. Eur J Med Chem. 2022 Dec 15;247:115001.
CAS Number
– 2650733-69-8
Molecular Weight
– 426.15
SMILES
– CN(C[C@@H](CN1C2=CC=C(C=C2C3=CC(Br)=CC=C31)Br)O)C
Clinical Information
– No Development Reported
Research Area
– Cancer; Metabolic Disease; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dynamin
Pathway
– Cytoskeleton
Product type
– Reference compound
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