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Products Details
Product Description
– AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ec50 value of ERK1/2 phosphorylation was 2 μM). AY 77 can promote migration of human breast cancer cells in vitro.
Web ID
– T41190
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H32N4O4
References
– Jiang Y, et al. Biased Signaling by Agonists of Protease Activated Receptor 2. ACS Chem Biol. 2017;12(5):1217-1226.
CAS Number
– 1835734-92-3
Molecular Weight
– C21H32N4O4
Compound Purity
– 0.997
SMILES
– [C@H](CC1CCCCC1)(C(N[C@H](C(N)=O)[C@@H]2CCCCC2)=O)NC(=O)C3=CC=NO3
Pathway
– Membrane transporter/Ion channel|||GPCR/G Protein|||Metabolism|||MAPK
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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