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Product Description
– AUNP-12 acetate is a polypeptide inhibitor of PD-1 that is equivalent to PD-1 and PD-2 in inhibiting lymphocyte proliferation and effector fuction, in addition to immune activation and antitumor activity.
Web ID
– TP1076L
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C144H230N40O50
References
– Pottayil G Sasikumar, et al. A Rationally Designed Peptide Antagonist of the PD-1 Signaling Pathway as an Immunomodulatory Agent for Cancer Therapy. Mol Cancer Ther. 2019 Jun;18(6):1081-1091.
Molecular Weight
– C144H230N40O50
Compound Purity
– 0.9507
SMILES
– O=C([C@@](C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])([H])N([H])C([C@](C([H])([H])[H])([H])N([H])C([C@@](C([H])([H])C([H])([H])C(N([H])[H])=O)([H])N([H])C([C@@]([C@@](C([H])([H])[H])([H])C([H])([H])C([H])([H])[H])([H])N([H])C([C@@](C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])([H])N([H])C([C@@](C([H])([H])C([H])([H])C(O[H])=O)([H])N([H])N([H])[H])=O)=O)=O)=O)=O)N1[C@@](C(N([H])[C@](C(C([C@@](C([H])([H])C(C([H])([H])[H])([H])C([H])([H])[H])([H])N([H])C([C@@](C([H])([H])C([H])([H])C(N([H])[H])=O)([H])N([H])C([C@@]([C@@](C([H])([H])[H])([H])O[H])([H])N([H])C([C@@](C(C([H])([H])[H])([H])C([H])([H])[H])([H])N([H])C([C@@](C([H])([H])C([H])([H])C([H])([H])N([H])/C(N([H])[H])=N/[H])([H])N([H])C([C@@](C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])([H])N([H])C(C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])N([H])[C@@](C(N([H])[C@](C([H])([H])O[H])([H])C(N([H])[C@@](C(N([H])[C@](C([H])([H])O[H])([H])C(N([H])[C@@](C(N([H])[C@@](C(N([H])[C@@](C([H])=O)([H])C([H])([H])O[H])=O)([H])C([H])([H])C(N([H])[H])=O)=O)([H])[C@@](C([H])([H])[H])([H])O[H])=O)=O)([H])C([H])([H])C([H])([H])C(O[H])=O)=O)=O)([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])([H])N([H])C([C@@](C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])([H])N([H])C([C@@](C([H])([H])O[H])([H])N([H])C([C@@](C([H])([H])C([H])([H])C(O[H])=O)([H])N([H])C([C@@](C([H])([H])O[H])([H])N([H])C([C@@]([C@@](C([H])([H])[H])([H])O[H])([H])N([H])C([C@@](C([H])([H])C(N([H])[H])=O)([H])N([H])C([C@@](C([H])([H])O[H])([H])N([H])[H])=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)([H])C([H])([H])[H])=O)([H])C([H])([H])C([H])([H])C1([H])[H].CC(O)=O
Pathway
– Apoptosis|||Immunology/Inflammation|||Cell Cycle/Checkpoint
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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