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Atipamezole (hydrochloride)
$60 – $312
Products Details
Product Description
– Atipamezole (MPV-1248) hydrochloride is a potent α2-adrenoceptor antagonist with a Ki of 1.6 nM[1].
Web ID
– HY-12380
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C14H17ClN2
Citations
– Protein Cell. 2019 Mar;10(3):178-195.|Brain Res. 2020 Sep 15;1743:146949.|Eur J Neurosci. 2021 Apr 27.|Exp Mol Pathol. 2021 Feb;118:104587.|Front Cell Dev Biol. 2021 Mar 11;9:636327.|Research Square Preprint. 2022 May.|Sci Transl Med. 2022 Nov 3;eabq4064.
References
– [1]Pertovaara A, et al.Pharmacological properties, central nervous system effects, and potential therapeutic applicationsof atipamezole, a selective alpha2-adrenoceptor antagonist. CNS Drug Rev. 2005 Autumn;11(3):273-88.
CAS Number
– 104075-48-1
Molecular Weight
– 248.75
Compound Purity
– 99.88
SMILES
– CCC1(C2=CN=CN2)CC3=C(C=CC=C3)C1.[H]Cl
Clinical Information
– Phase 1
Research Area
– Neurological Disease; Endocrinology
Solubility
– DMSO : ≥ 47 mg/mL|H2O : 75 mg/mL (ultrasonic;warming)
Target
– Adrenergic Receptor
Isoform
– α adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
