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Products Details
Product Description
– Antitumor agent-57 (Compound 3o) is an NQO1-directed antitumor agent. Antitumor agent-57 inhibits tumor cell growth, triggers ROS generation and induces cell apoptosis[1].
Web ID
– HY-146048
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H15NO5
References
– [1]Wu LQ, et al. Design, synthesis, and biological evaluation of 4-substituted-3,4-dihydrobenzo[h]quinoline-2,5,6(1H)-triones as NQO1-directed antitumor agents. Eur J Med Chem. 2020 Jul 15;198:112396.
CAS Number
– 2432823-48-6
Molecular Weight
– 349.34
SMILES
– O=C1NC2=C(C(C(C3=CC=CC=C32)=O)=O)C(C4=CC=C(OC)C(O)=C4)C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Reactive Oxygen Species
Pathway
– Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
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