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Products Details
Product Description
– Antiproliferative agent-4 (compound 2y) has excellent anti-proliferative activity against certain cancer cell lines. Antiproliferative agent-4 reduces the mitochondrial membrane potential, and increases the apoptosis rate and the level of ROS on EC109. Antiproliferative agent-4 inhibits tumour growth in nude mice, with low toxicity[1].
Web ID
– HY-146354
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C29H35ClO8
References
– [1]Huo JF, et al. Synthesis and in vitro and in vivo biological evaluation of novel derivatives of flexicaulin A as antiproliferative agents. Eur J Med Chem. 2020;208:112789.
Molecular Weight
– 547.04
SMILES
– CC1(C)CCC[C@]2(COC(O)=O)C1C[C@@H](O)[C@]3(C4=O)C2[C@@H](O)C[C@@H](C4=C)[C@H]3OC(C5=CC=C(CCl)C=C5)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Reactive Oxygen Species
Pathway
– Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
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