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Products Details
Product Description
– Antiproliferative agent-11 (compound 7) is an antiproliferative and selective Ruthenium(II)-Tris-pyrazolylmethane complex. Antiproliferative agent-11 shows antiproliferative activity towards MCF-7, HeLa, 518A2, HCT116 and RD with IC50s of 6, 10, 6.8, 6.7 and 6 μM, respectively. Antiproliferative agent-11 can be used for the research of cancer[1].
Web ID
– HY-150968
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C31H34Cl2N6O3P2Ru
References
– [1]Cervinka J, et al. Ruthenium(II)-Tris-pyrazolylmethane Complexes Inhibit Cancer Cell Growth by Disrupting Mitochondrial Calcium Homeostasis. J Med Chem. 2022 Aug 1.
Molecular Weight
– 772.56
SMILES
– [H]c12n3cccn3[Ru+](n4n2ccc4)(Cl)([P](C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)([P](OC)(OC)OC)n8n1ccc8.[Cl-]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
