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Products Details
Product Description
– Antimalarial agent 7 is a potent inhibitor of PfATP4. PfATP4 is an essential ion pump on the parasite surface. Antimalarial agent 7 has the potential for the research of human malaria parasite, Plasmodium falciparum[1].
Web ID
– HY-145327
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H22F2N4O3
References
– [1]Tse EG, et al. An Open Drug Discovery Competition: Experimental Validation of Predictive Models in a Series of Novel Antimalarials. J Med Chem. 2021;64(22):16450-16463.
CAS Number
– 2756414-77-2
Molecular Weight
– 440.44
SMILES
– CC(C)(OC1=CC=C(C=C1)C2=NN=C3C=NC=C(N32)OCC(C4=CC(F)=C(C=C4)F)O)C
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Na+/K+ ATPase;Parasite
Isoform
– Plasmodium
Pathway
– Anti-infection;Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
