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Products Details
Product Description
– AChE-IN-25 is a potent, selective and uncompetitive acetylcholinesterase (AChE) inhibitor (IC50=2.95 µM). AChE-IN-25 can be used in Alzheimer’s disease research[1].
Web ID
– HY-151338
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C20H15ClN4O4S
References
– [1]Hormoz Pourtaher, et al. Design, synthesis, in silico and biological evaluations of novel polysubstituted pyrroles as selective acetylcholinesterase inhibitors against Alzheimer’s disease. Sci Rep. 2022 Sep 8;12(1):15236.
CAS Number
– 2835538-69-5
Molecular Weight
– 442.88
SMILES
– O=C(N)C(C1=C(C2=CC=C(Cl)C=C2)N(C3=CC=C(O)C=C3)C(SC)=C1[N+]([O-])=O)C#N
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Isoform
– AChE
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
