Download Files:
Products Details
Product Description
– AChE-IN-24 is a potent AChE inhibitor and can penetrate the BBB. AChE-IN-24 has the mighty inhibitory activity to hAChE with an IC50 value of 0.053 μM. AChE-IN-24 can be used for the research of Alzheimer s disease (AD)[1].
Web ID
– HY-151152
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C22H30N2O4S2
References
– [1]Jie Guo, et al. A multi-target directed ligands strategy for the treatment of Alzheimer’s disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator. Eur J Med Chem. 2022 Aug 11;242:114630.
Molecular Weight
– 450.61
SMILES
– O=C(OC)/C=C/C(NC1=CC=CC(OCCCCSC(N2C(C)CCCC2)=S)=C1)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Isoform
– AChE
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
