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AC-VEID-CHO (TFA)
$350
Only 1000 item(s) left in stock.
Products Details
Product Description
– AC-VEID-CHO (TFA) is a peptide-derived caspase inhibitor and has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 with IC50 values of 16.2 nM, 13.6 nM and 162.1 nM, respectively. AC-VEID-CHO (TFA) can be used for the research of neurodegenerative conditions including Alzheimer’s and Huntington’s disease[1].
Web ID
– HY-108312A
Storage Temperature
– -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C24H37F3N4O11
References
– [1]Robert Mintzer, et al. A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C. PLoS One. 2012;7(1):e30376.
Molecular Weight
– 614.57
Compound Purity
– 98.0
SMILES
– OC(C(F)(F)F)=O.CC[C@@H]([C@@H](C(N[C@H](C=O)CC(O)=O)=O)NC([C@@H](NC([C@H](C(C)C)NC(C)=O)=O)CCC(O)=O)=O)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– H2O : 1 mg/mL (ultrasonic;warming)
Target
– Caspase
Isoform
– Caspase 3;Caspase 6;Caspase 7
Pathway
– Apoptosis
Product type
– Peptides
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
