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Products Details
Product Description
– 8-NH2-ATP, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado is reported to be potent as shown by induction of apoptosis-related cleavage of poly (ADP-ribose) polymerase[1][2].
Web ID
– HY-134313
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C10H17N6O13P3
References
– [1]Nancy L Krett, et al. 8-amino-adenosine is a potential therapeutic agent for multiple myeloma. Mol Cancer Ther. 2004 Nov;3(11):1411-20.|[2]Yuji Matsuzaki, et al. ATP-association to intrabacterial nanotransportation system in Vibrio cholera. Med Mol Morphol. 2015 Dec;48(4):225-34.
CAS Number
– 35874-49-8
Molecular Weight
– 522.20
SMILES
– NC(N([C@]([C@@H]([C@@H]1O)O)([H])O[C@@H]1CO[P](O[P](O[P](O)(O)=O)(O)=O)(O)=O)C2=NC=N3)=NC2=C3N
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis;Endogenous Metabolite
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
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