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Products Details
Product Description
– (1R,3S)-THCCA-Asn (4j) is a selective thrombin inhibitor with the IC50 value in the range of 0.07 to 0.14 μM. ((1R,3S)-THCCA-Asn has antithrombotic activity[1].
Web ID
– HY-151146
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C24H24N4O6
References
– [1]Xiaoyi Zhang, et al. (1R,3S)-THCCA-Asn: To show the discovery of selective inhibitor of thrombin by successfully combining virtual screening and biological assay,European Journal of Medicinal Chemistry,Volume 242,2022,114681.
Molecular Weight
– 464.47
SMILES
– OC1=CC=C([C@H]2N[C@@H](CC3=C2NC4=C3C=CC=C4)C(N[C@@H](CC(N)=O)C=O)=O)C=C1C(OC)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Thrombin
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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