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(1R,2S)-VU0155041

$84$264

Products Details

Product Description

– (1R,2S)-VU0155041, Cis regioisomer of VU0155041, is a partial mGluR4 agonist with an EC50 of 2.35 μM.

Web ID

– HY-14417A

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C14H15Cl2NO3

References

– [1]Niswender CM, et al. Discovery, characterization, and antiparkinsonian effect of novel positiveallosteric modulators of metabotropic glutamate receptor 4. Mol Pharmacol. 2008 Nov;74(5):1345-58.

CAS Number

– 1263273-14-8

Molecular Weight

– 316.18

Compound Purity

– 98.0

SMILES

– O=C([C@H]1[C@@H](C(NC2=CC(Cl)=CC(Cl)=C2)=O)CCCC1)O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– DMSO : 50 mg/mL (ultrasonic)

Target

– mGluR

Isoform

– mGluR4

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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