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18-Oxocortisol
$720
Only 1000 item(s) left in stock.
Products Details
Product Description
– 18-Oxocortisol is a derivative of cortisol that is produced by aldosterone synthase (CYP11B2). 18-Oxocortisol is a naturally occurring mineralocorticoid agonist. 18-Oxocortisol is a biomarker in adrenal vein sampling[1][2][3].
Web ID
– HY-113151
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H28O6
References
– [1]Nakamura Y, et al. 18-oxocortisol measurement in adrenal vein sampling as a biomarker for subclassifying primaryaldosteronism. J Clin Endocrinol Metab. 2011 Aug;96(8):E1272-8.|[2]Ulick S, et al. 18-oxocortisol, a naturally occurring mineralocorticoid agonist. Endocrinology. 1983 Dec;113(6):2320-2.
CAS Number
– 2410-60-8
Molecular Weight
– 376.44
Compound Purity
– 98.0
SMILES
– O=C1CC[C@]2(C)[C@@]3([H])[C@@H](O)C[C@]4(C=O)[C@](C(CO)=O)(O)CC[C@@]4([H])[C@]3([H])CCC2=C1
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite;Mineralocorticoid Receptor
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
