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1′-Hydroxy bufuralol
$760 – $1,220
Products Details
Product Description
– 1′-Hydroxy bufuralol, the main metabolite of bufuralol, can reflect CYP2D activity[1].
Web ID
– HY-122277
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C16H23NO3
References
– [1]Evangelos P Daskalopoulos, et al. Dâ‚‚-dopaminergic receptor-linked pathways: critical regulators of CYP3A, CYP2C, and CYP2D. Mol Pharmacol. 2012 Oct;82(4):668-78.|[2]H Yamazaki, et al. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes. Mol Pharmacol. 1994 Sep;46(3):568-77.
CAS Number
– 57704-16-2
Molecular Weight
– 277.36
Compound Purity
– 97.0
SMILES
– CC(C1=C2OC(C(CNC(C)(C)C)O)=CC2=CC=C1)O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Cytochrome P450
Isoform
– CYP2
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
