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T-3775440 hydrochloride
$320 – $2,350
Products Details
Product Description
– T-3775440 (hydrochloride) is an irreversible lysine-specific histone demethylase (LSD1) inhibitor with an IC50 value of 2.1 nM.
Web ID
– HY-103085
Storage Temperature
– 4°C (Powder, stored under nitrogen, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H23ClN4O
References
– [1]Ishikawa Y, et al. A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells. Mol Cancer Ther. 2017 Feb;16(2):273-284.
CAS Number
– 1422535-52-1
Molecular Weight
– 346.85
Compound Purity
– 99.13
SMILES
– O=C(NC1=CC=C([C@@H]2C[C@H]2NCC3CC3)C=C1)C4=CN(C)N=C4.Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 30.18 mg/mL|H2O : 8.33 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Histone Demethylase
Isoform
– KDM1/LSD1
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
