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Topoisomerase II alpha (Proliferation & Drug-Resistance Marker) (TOP2A/1361), CF740 conjugate, 0.1mg/mL

SKU BT-A-BNC741361 Categories Biotium Antibodies, Cell cycle Brand: Biotium

Price range: 328 CAD through 896 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.Intended for use by research organizations and laboratories only; not for patients or for personal use.

Size

100 μL 500 μL

Clear

Products Details

Product Description

–

This antibody recognizes a 170 kDa protein, which is identified as topoisomerase IIα. It shows no cross-reaction with topoisomerase IIβ or topoisomerase I. Topo IIα plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo IIα is also implicated in drug resistance of tumor cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, [cosmetic chemistry research literature], or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Storage Temperature

– 2-8 °C (Refrigerator)

Shipping

– Room temperature

Applications

– IF (verified), IHC, FFPE (verified), WB (verified)

Antibody Type

– Primary

Antibody Host

– Mouse

Antibody Isotype

– IgG2b, kappa

Molecular Weight

Clinical Information

– HeLa Cells or Tonsil

Research Area

– Cell cycle

Target

– Topoisomerase-II-Alpha

Product type

– Primary Antibody

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.