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Interferon alpha-2 (IFNA2)(N39), CF594 conjugate, 0.1mg/mL
318 CAD – 882 CADPrice range: 318 CAD through 882 CAD
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This antibody recognizes a protein of 16-27 kDa, identified as human interferon-alpha-2 (IFN-a2). Its epitope maps between aa112-148 of IFN-a2 (total aa172). This MAb is specific for IFN-a2 and does not cross-react with interferon-alpha-1. The site recognized by this MAb is called site I and is responsible for the antiviral and anti-proliferative activities of IFN-a2. Epitopes of N27 and N39 MAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-a2 after viral infections. The IFN-a family consists of 24 or more genes or pseudo-genes. IFN-a2 is one of the two distinct families (I and II) of human IFN-a. The alpha-interferons are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.
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Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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