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c-Myc Oncoprotein(MYC275 + MYC909), 0.2mg/mL

SKU BT-A-BNUB1269 Categories Biotium Antibodies, Cancer, Cell cycle, Transcription factors Brand: Biotium

Price range: 373 CAD through 803 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.Intended for use by research organizations and laboratories only; not for patients or for personal use.

Size

100 μL 500 μL

Clear

Products Details

Product Description

–

This antibody recognizes a transcription factor of 64-67 kDa, identified as c-myc. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or over-expressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease. Rearrangement of the MYC gene is found in 3% to 16% of diffuse large B-cell lymphoma (DLBCL’s) and in nearly 100% of Burkitt lymphomas (BL). Identifying MYC status is important in establishing final diagnosis of DLBCL, BL, or B-cell lymphoma, with features intermediate between DLBCL and BL as well as in differential diagnoses of the lymphomas.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, [cosmetic chemistry research literature], or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Storage Temperature

– 2-8 °C (Refrigerator)

Shipping

– Room temperature

Applications

– IHC, FFPE (verified)

Antibody Type

– Primary

Antibody Host

– Mouse

Antibody Isotype

– IgG1, kappa

Molecular Weight

Clinical Information

– HL-60 cells. Cervical Carcinoma.

Research Area

– Cancer, Cell cycle, Transcription factors

Target

– c-Myc

Product type

– Primary Antibody

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.