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Products Details
Product Description
– GT-2016 is a potent, selective, and brain penetrant histamine H3 receptor antagonist with a Ki of 43.8 nM. GT-2016 displays selectivity against H1 and H2 receptors, and has non-active against histamine methyltransferase[1].
Web ID
– HY-107559
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C19H31N3O
References
– [1]C E Tedford, et al. Pharmacological characterization of GT-2016, a non-thiourea-containing histamine H3 receptor antagonist: in vitro and in vivo studies. J Pharmacol Exp Ther. 1995 Nov;275(2):598-604.
CAS Number
– 152241-24-2
Molecular Weight
– 317.47
SMILES
– O=C(N1CCC(C2=CNC=N2)CC1)CCCCC3CCCCC3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Histamine Receptor
Isoform
– H3 Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
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