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Products Details
Product Description
– ZD-9379 is a potent, orally active, and brain penetrant full antagonist at the glycine site of the NMDA receptor. ZD-9379 has neuroprotective effect[1][2].
Web ID
– HY-106968
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C19H14ClN3O4
References
– [1]Tatlisumak T, et al. A glycine site antagonist, ZD9379, reduces number of spreading depressions and infarct size in rats with permanent middle cerebral artery occlusion. Stroke. 1998;29(1):190-195.|[2]ZD 9379. Drugs R D. 1999;1(1):44-45.
CAS Number
– 170142-20-8
Molecular Weight
– 383.79
SMILES
– O=C1C2=C(C(NN1C3=C(C=C(OC)C=C3)C)=O)NC4=C(C=CC(Cl)=C4)C2=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– iGluR
Isoform
– NMDA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
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