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CARM1-IN-1 (hydrochloride)
$100 – $600
Products Details
Product Description
– CARM1-IN-1 hydrochloride is a potent and specific CARM1 (Coactivator-associated arginine methyltransferase 1) inhibitor with IC50 of 8.6 uM; shows very low activity against PRMT1 and SET7.
Web ID
– HY-12759A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H22Br2ClNO3
References
– [1]Cheng D, et al. Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity. J Med Chem. 2011 Jul 14;54(13):4928-32.
CAS Number
– 2070018-31-2
Molecular Weight
– 591.72
Compound Purity
– 95.16
SMILES
– [H]Cl.O=C1/C(CN(CC2=CC=CC=C2)C/C1=CC3=CC=C(O)C(Br)=C3)=C/C4=CC=C(O)C(Br)=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 250 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL
Target
– Histone Methyltransferase
Isoform
– PRMT4
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
