![](https://immunomart.com/wp-content/uploads/2024/03/HY-111845.gif)
Download Files:
Estrone-N-O-C1-amido
SKU
HY-111845-Get quote
Category Reference compound
Tags Cancer, Estrogen Receptor/ERR;Ligands for Target Protein for PROTAC, PROTAC;Vitamin D Related/Nuclear Receptor
Products Details
Product Description
– Estrone-N-O-C1-amido (ERα ligand 1) is an Estrone-based estrogen ligand, which targets estrogen receptor α (ERα). Estrone-N-O-C1-amido (ERα ligand 1) binds to cIAP1 ligand Bestatin via a linker to form SNIPER[1].
Web ID
– HY-111845
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H26N2O3
References
– [1]Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176.
CAS Number
– 138219-84-8
Molecular Weight
– 342.43
SMILES
– O=C(N)CO/N=C1CC[C@]2([H])[C@]1(C)CC[C@@]3([H])[C@@]2([H])CCC4=C3C=CC(O)=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Estrogen Receptor/ERR;Ligands for Target Protein for PROTAC
Pathway
– PROTAC;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.