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Products Details
Product Description
– Triclabendazole sulfoxide (TCBZ-SO) is the main plasma metabolite of Triclabendazole, and exhibits anti-parasite effects. Triclabendazole sulfoxide can inhibit membrane transporter ABCG2/BCRP[1][2].
Web ID
– HY-136450
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C14H9Cl3N2O2S
References
– [1]Barrera B, et, al. The anthelmintic triclabendazole and its metabolites inhibit the membrane transporter ABCG2/BCRP. Antimicrob Agents Chemother. 2012 Jul;56(7):3535-43.|[2]Robinson MW, et, al. The comparative metabolism of triclabendazole sulphoxide by triclabendazole-susceptible and triclabendazole-resistant Fasciola hepatica. Parasitol Res. 2004 Feb;92(3):205-10.
CAS Number
– 100648-13-3
Molecular Weight
– 375.66
SMILES
– O=S(C1=NC2=CC(OC3=CC=CC(Cl)=C3Cl)=C(Cl)C=C2N1)C
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– BCRP;Parasite
Pathway
– Anti-infection;Membrane Transporter/Ion Channel
Product type
– Reference compound
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