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TNKS-2-IN-1
46 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.TNKS-2-IN-1 inhibits the release of IL-1β from the NLRP3 inflammasome (IC50: 5 μM) by inhibiting IL-1β release from ATP-stimulated J1A.774 cells.
Web ID
– T77675
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C14H9N3O3
References
– Nathubhai A, et al. Structure-activity relationships of 2-arylquinazolin-4-ones as highly selective and potent inhibitors of the tankyrases. Eur J Med Chem. 2016 Aug 8;118:316-27.
CAS Number
– 4765-59-7
Molecular Weight
– C14H9N3O3
Compound Purity
– 0.984
SMILES
– [O-][N+](=O)c1ccc(cc1)-c1nc(=O)c2ccccc2[nH]1
Pathway
– Cytoskeletal Signaling|||Stem Cells|||Microbiology/Virology|||DNA Damage/DNA Repair|||Chromatin/Epigenetic
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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