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Lersivirine
$75 – $1,584
Products Details
Product Description
– Lersivirine (UK-453061) is potent and selective non-nucleoside reverse transcription inhibitor (NNRTI; IC50=119 nM) with excellent efficacy against NNRTI-resistant viruses. Lersivirine exhibits potent antiretroviral activity against wild-type HIV virus and clinically relevant NNRTI-resistant strains[1].
Web ID
– HY-14267
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C17H18N4O2
References
– [1]Mowbray CE, et al. Pyrazole NNRTIs 4: selection of UK-453,061 (lersivirine) as a development candidate. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5857-60.|[2]Gregg D Cappon, et al. Developmental toxicity study of lersivirine in mice. Birth Defects Res B Dev Reprod Toxicol. 2012 Jun;95(3):225-30.
CAS Number
– 473921-12-9
Molecular Weight
– 310.35
Compound Purity
– 98.33
SMILES
– CCC1=NN(CCO)C(CC)=C1OC2=CC(C#N)=CC(C#N)=C2
Clinical Information
– Phase 2
Research Area
– Infection
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– HIV;Reverse Transcriptase
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
