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L524-0366

SKU T8570-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 214 CAD through 2,320 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– L524-0366 ([1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone) is a TWEAK-Fn14 signaling cascade inhibitor.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T8570

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C13H13ClN4OS

Citations

– 1. Li Z, Wang H, Zhu J, et al. Inhibition of TWEAK/Tnfrsf12a axis protects against acute liver failure by suppressing RIPK1-dependent apoptosis. Cell Death Discovery. 2022, 8(1): 1-11 2. Liu L, Wu P, Wei Y, et al.TWEAK-Fn14 signaling protects mice from pulmonary fibrosis by inhibiting fibroblast activation and recruiting pro-regenerative macrophages.Cell Reports.2025, 44(2).

References

– Unudurthi S D , Nassal D M , Patel N J , et al. Fibroblast growth factor-inducible 14 mediates macrophage infiltration in heart to promote pressure overload-induced cardiac dysfunction[J]. Life ences, 2020, 247:117440.

CAS Number

– 951612-19-4

Molecular Weight

– C13H13ClN4OS

Compound Purity

– 0.986

SMILES

– C(=O)(C1=CN(N=N1)C2=CC(Cl)=CC=C2)N3CCSCC3

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.