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Doxifluridine

SKU T1600-1 g Category Small Compound Brand: TargetMol

Price range: 64 CAD through 150 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 g 5 g

Clear

Products Details

Product Description

– Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation of 5-FU by dihydropyrimidine dehydrogenase in the gut wall, is converted into 5-FU in the presence of pyrimidine nucleoside phosphorylase. 5-FU interferes with DNA synthesis and subsequent cell division by reducing normal thymidine production and interferes with RNA transcription by competing with uridine triphosphate for incorporation into the RNA strand.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1600

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C9H11FN2O5

Citations

– 1. Doxifluridine promotes host longevity through bacterial metabolism

References

– Naganuma Y, et al. Cancer Sci,2011, 102(8), 1545-1552.

CAS Number

– 3094-09-5

Molecular Weight

– C9H11FN2O5

Compound Purity

– 0.9947

SMILES

– O[C@H]1[C@@H](O[C@H](C)[C@H]1O)N2C(=O)NC(=O)C(F)=C2

Pathway

– Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.