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Products Details
Product Description
– Anti-inflammatory agent 33 is a potent p38α inhibitor. Anti-inflammatory agent 33 inhibits NO production. Anti-inflammatory agent 33 inhibits LPS-induced iNOS, COX-2, p-p38α, p-MK2 protein expression. Anti-inflammatory agent 33 shows anti-inflammatory activity[1].
Web ID
– HY-151921
Shipping
– Room temperature
Molecular Formula
– C22H15N3O5S
References
– [1]Du J, et al. Novel tryptanthrin derivatives with benzenesulfonamide substituents: Design, synthesis, and anti-inflammatory evaluation. Eur J Med Chem. 2022 Nov 25;246:114956.
CAS Number
– 2816993-09-4
Molecular Weight
– 433.44
SMILES
– COC1=CC=C(C=C1)S(=O)(NC2=CC3=C(N=C4C(C5=CC=CC=C5N4C3=O)=O)C=C2)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– p38 MAPK
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
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